Surgical management of early stage cervical cancer: ten years experience from one Greek health region (Journal article)

Paraskevaidis, E./ Kalantaridou, S. N./ Kaponis, A./ Chouliara, S./ Agnantis, N. J./ Dousias, V./ Zikopoulos, K./ Paschopoulos, M./ Stamatopoulos, P./ Lolis, D. E.


PURPOSE OF INVESTIGATION: Cervical cancer is the second most common malignancy in women, in both incidence and mortality. In the present study, we report our results of treating 93 consecutive patients with early invasive cervical cancers (Stages I-IIA). METHODS: The patients of this study comprised all women recognized with stage I-IIA cervical cancer during 1991-2000. Patients with stage IA1 cervical cancer without lymphvascular space involvement underwent either conservative management by means of large loop conization or simple hysterectomy. The remaining patients underwent radical hysterectomy and lymphadenectomy or radiation therapy. Mean (+/- SD) duration of follow-up was 6 (+/- 1.7) years. RESULTS: The mean (+/- SD) age of patients with stage I-IIA cervical cancer was 41.3 (+/- 9.1) year. Thirty-five patients with stage [A1 disease were managed conservatively with loop excision and 19 patients subsequently became pregnant. Fifty-two patients with stage IA2, IB and IIA cervical carcinoma underwent radical hysterectomy and lymphadenectomy. CONCLUSION: Young women with stage IA1 cervical carcinoma wishing future fertility who undergo loop excision have a 100% cure rate. Women with stage IA2, IB, and IIA cervical cancer should undergo radical hysterectomy and lymphadenectomy or radiation therapy.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adult,Conization,Female,Greece/epidemiology,Humans,Hysterectomy,Incidence,Lymph Node Excision,Middle Aged,Neoplasm Staging,Pregnancy,Pregnancy Outcome,Radiotherapy, Adjuvant,Uterine Cervical,Neoplasms/*epidemiology/etiology/mortality/pathology/radiotherapy/*surgery
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/17971
ISSN: 0392-2936
Link: http://www.ncbi.nlm.nih.gov/pubmed/12214740
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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