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https://olympias.lib.uoi.gr/jspui/handle/123456789/17738Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Nikas, D. N. | en |
| dc.contributor.author | Kalef-Ezra, J. | en |
| dc.contributor.author | Katsouras, C. S. | en |
| dc.contributor.author | Tsekeris, P. | en |
| dc.contributor.author | Bozios, G. | en |
| dc.contributor.author | Pappas, C. | en |
| dc.contributor.author | Naka, K. K. | en |
| dc.contributor.author | Kotsia, A. | en |
| dc.contributor.author | Papamichael, N. | en |
| dc.contributor.author | Sideris, D. A. | en |
| dc.contributor.author | Michalis, L. K. | en |
| dc.date.accessioned | 2015-11-24T18:42:09Z | - |
| dc.date.available | 2015-11-24T18:42:09Z | - |
| dc.identifier.issn | 0167-5273 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/17738 | - |
| dc.rights | Default Licence | - |
| dc.subject | percutaneous coronary interventions | en |
| dc.subject | beta-brachytherapy | en |
| dc.subject | intravascular brachytherapy | en |
| dc.subject | in-stent restenosis | en |
| dc.subject | intracoronary gamma-radiation | en |
| dc.subject | catheter-based radiotherapy | en |
| dc.subject | 2-year follow-up | en |
| dc.subject | intravascular ultrasound | en |
| dc.subject | coronary restenosis | en |
| dc.subject | washington radiation | en |
| dc.subject | balloon angioplasty | en |
| dc.subject | late thrombosis | en |
| dc.subject | wrist-plus | en |
| dc.title | Long-term clinical outcome of patients treated with beta-brachytherapy in routine clinical practice | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | DOI 10.1016/j.ijcard.2006.03.008 | - |
| heal.identifier.secondary | <Go to ISI>://000244512800008 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0167527306003883/1-s2.0-S0167527306003883-main.pdf?_tid=5c502d60-ada2-11e2-92d1-00000aab0f6b&acdnat=1366892542_de869a53bb347fae9b03a85b75d6268d | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιών | el |
| heal.publicationDate | 2007 | - |
| heal.abstract | Background: Only limited data exist regarding the long-term efficacy of beta-brachytherapy (beta-VBT) in routine clinical practice and the impact of the prolonged (> 6 months) combined antiplatelet therapy after beta-VBT. Our aim is to examine the long-term clinical efficacy of routine beta brachytherapy (beta-VBT) followed by indefinite administration of combined antiplatelet therapy in patients at high restenotic risk. Methods: Sixty-one patients with 65 lesions [de novo: 41, in-stent restenotic (ISR): 24] underwent intracoronary beta-VBT and were followed prospectively. All patients received indefinite administration of aspirin and clopidogrel, underwent routine angiography 6 months later and were followed-up clinically for 43.7 months (range: 32 to 52 months). Results: Acute success was achieved in 60/61 (98.4%) patients. Lesion length was 36.1 (+/- 17.6) mm for the de novo and 22.0 (+/- 9.8) mm for the ISR (p=0.001). Stems were implanted in 35/41 de novo and 7/24 ISR lesions (p < 0.01). Six-month binary restenosis after successful beta-VBT was 35.9% (23/64). During follow-up patients with de-novo lesions who received a new stent during index procedure had a higher incidence of major cardiac events than patients with ISR lesions without a new stent (log rank test, p=0.02). Acute and late thrombotic events were reported at 6 patients, all with de novo lesions and stent implantation. Conclusions: Beta-VBT plus stenting in de novo lesions is related to an unacceptable high rate of thrombotic complications and clinical restenosis despite prolonged administration of combined antiplatelet therapy. Brachytherapy remains a reasonable option for patients with ISR lesions until full data from large randomized trials comparing drug eluting stents with brachytherapy are available. (c) 2006 Elsevier Ireland Ltd. All rights reserved. | en |
| heal.journalName | Int J Cardiol | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Nikas-2007-Long-term clinical o.pdf | 132.52 kB | Adobe PDF | View/Open Request a copy |
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