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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kalogeras, D. | en |
| dc.contributor.author | Lampri, E. | en |
| dc.contributor.author | Goussia, A. | en |
| dc.contributor.author | Bai, M. | en |
| dc.contributor.author | Capizzello, A. | en |
| dc.contributor.author | Tassiou, I. | en |
| dc.contributor.author | Stavropoulos, N. E. | en |
| dc.contributor.author | Tsekeris, P. | en |
| dc.date.accessioned | 2015-11-24T18:38:09Z | - |
| dc.date.available | 2015-11-24T18:38:09Z | - |
| dc.identifier.issn | 1107-0625 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/17288 | - |
| dc.rights | Default Licence | - |
| dc.subject | age | en |
| dc.subject | bladder cancer | en |
| dc.subject | cystectomy | en |
| dc.subject | muscle-infiltrating | en |
| dc.subject | radiotherapy | en |
| dc.subject | survival | en |
| dc.subject | transitional-cell carcinoma | en |
| dc.subject | ileal conduit diversion | en |
| dc.subject | term-follow-up | en |
| dc.subject | neoadjuvant chemotherapy | en |
| dc.subject | survival | en |
| dc.subject | preservation | en |
| dc.subject | complications | en |
| dc.subject | metastases | en |
| dc.subject | radiation | en |
| dc.subject | prostate | en |
| dc.title | Radical therapy for muscle-infiltrating bladder cancer (cystectomy or radiotherapy): does age affect the final therapeutic benefit for the patient? | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | <Go to ISI>://000259689200006 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιών | el |
| heal.publicationDate | 2008 | - |
| heal.abstract | Purpose: To evaluate the therapeutic outcome of radical cystectomy and radical radio therapy in patients with T2N0M0 clinical stage bladder cancer in relation to their age. Patients and methods: Between 1995-2006, 119 patients with clinical stage T2N0M0 bladder cancer were treated with radical radiotherapy (group A) and were divided in 2 subgroups: > 70 years old(A1) and <= 70 years old (A2). Between 1998-2006, 26 patients with the same clinical stage were treated with radical cystectomy (group B) (> 70 years old/B1 subgroup and <= 70 years old/B2 subgroup). The following parameters were evaluated in both groups and subgroups: therapeutic outcome (overall survival/OS, local control, development of metastases) and tolerance (side effects and complications of each method). Kaplan-Meier method and log-rank test were used for statistical analyses. Results: All group B patients tolerated their treatment very well, without interruptions. The 3-year OS of groups A and B was 39 and 69%, respectively (p= 0.032). The 3-year OS of subgroups A I and A 2 was 37.3 and 43.3%, respectively (p= 0.085). In the cystectomy group B, 3-year OS of the subgroups was the same (B1: 68.6% and B2: 69.3%; p= 0.10). Local control rate for the subgroups A1, A2, B1, B2 was 43, 40, 90 and 84%, respectively. Distant metastatic rate was 14.1, 20, 7.6 and 7.4% for subgroups A1, A2, B1, B2, respectively. Conclusion: The results of both therapeutic methods in both age groups seem satisfactory. Very good tolerance was also observed. It seems that if a patient is not completely suitable for radical cystectomy or radical radiotherapy age should not be considered as an exclusion factor. | en |
| heal.journalName | Journal of Buon | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) | |
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