Complementary peptide epitopes and anti-idiotypic antibodies in autoimmunity (Journal article)

Sakarellos-Daitsiotis, M./ Cung, M. T./ Sakarellos, C./ El Hilali, Z./ Kosmopoulou, A./ Voitharou, C.

Application of complementary B and T cell epitopes in inducing anti-idiotypic and anticlonotypic antibodies capable of regulating or suppressing the autoimmune responses in experimental autoimmune myasthenia gravis (EAMG), allergic neuritis (EAN) and allergic encephalomyelitis (EAE) has been the stimulus of many research efforts. Studies on the idiotypic/anti-idiotypic network of anti-La/SSB positive sera from patients with Sjogren's Syndrome (SS) and Systemic Lupus Erythematous (SLE) and oil animals immunized with the complementary epitopes are presented.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας
Keywords: complementary epitopes,autoimmune diseases,anti-idiotypic antibodies,experimental allergic neuritis,main immunogenic region,acetylcholine-receptor,myasthenia-gravis,messenger-rna,b-cell,protein,autoantibodies,binding,encephalomyelitis
ISSN: 0929-8665
Link: <Go to ISI>://000222704000012
Publisher: Bentham Science Publ Ltd.
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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