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dc.contributor.authorRoutsias, J. G.en
dc.contributor.authorTzioufas, A. G.en
dc.contributor.authorSakarellos-Daitsiotis, M.en
dc.contributor.authorSakarellos, C.en
dc.contributor.authorMoutsopoulos, H. M.en
dc.date.accessioned2015-11-24T16:53:22Z-
dc.date.available2015-11-24T16:53:22Z-
dc.identifier.issn0009-9104-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/10007-
dc.rightsDefault Licence-
dc.subjectcalreticulinen
dc.subjectro/ssaen
dc.subjectautoimmune rheumatic diseasesen
dc.subjectsynthetic peptidesen
dc.subjectcalcium-binding proteinen
dc.subjectro/ss-a autoantigenen
dc.subjectro ribonucleoproteinen
dc.subjectlupus-erythematosusen
dc.subjectmolecular-cloningen
dc.subjectparticleen
dc.subjectsequenceen
dc.subjectheterogeneityen
dc.subjectcalregulinen
dc.subjectcomponenten
dc.titleCalreticulin Synthetic Peptide Analogs - Antipeptide Antibodies in Autoimmune Rheumatic Diseasesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondary<Go to ISI>://A1993KP26700016-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1111/j.1365-2249.1993.tb05921.x/asset/j.1365-2249.1993.tb05921.x.pdf?v=1&t=h0e0qi0o&s=25c3969a70c18d624a2d8c3f16a35c94a6eb5d76-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate1993-
heal.abstractAutoantibodies in sera from patients with systemic lupus erythematosus (SLE) and onchocerciasis recognize calreticulin (CaR), a calcium-binding protein, as antigen. In this study we present the immunological properties of two synthetic peptides prepared to correspond to the 1-24 and 7-24 amino acid sequence of CaR. In contrast to information previously reported for the recombinant protein, the CaR-peptide analogues appeared immunoreactive to anti-Ro/SSA autoimmune sera. Human sera from patients with SLE, Sjogren's syndrome (SS), rheumatoid arthritis (RA), as well as mixed connective tissue disease (MCTD), demonstrated a positive autoimmune response (binding of antibodies), to the CaR-peptide analogues. These findings suggest that anti-calreticulin autoantibodies are not restricted to any disease specificity.en
heal.publisherBlackwellen
heal.journalNameClin Exp Immunolen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ

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